1627122-26-2

JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in Tau-overexpressing HeLa cells, endogenous Tau in neuroblastoma cells, and endogenous Tau in primary neurons from rTg4510 mice, a mouse model of Alzheimer’s disease

JG-48 是一种 Hsp70 抑制剂，可以降低 tau 蛋白病模型中的 tau 水平。