155294-62-5
基本信息
(E)-3-([3,3'-联噻吩]-5-基甲氧基)-N-(6,6-二甲基-2-庚烯-4-炔基)-N-乙基苯甲胺马来酸盐
NB 598
NB598 Maleate
NB 598 Maleate
NB-598 (Maleate)
(E)-3-([3,3'-Bithiophen]-5-ylmethoxy)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-ethyl-benzenemethanamine (Z)-2-butenedioate (1:1)
物理化学性质
| 储存条件 | -20°C储存 |
| 溶解度 | DMSO : 100 mg/mL (176.76 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| 形态 | 粉末 |
| 颜色 | Off-white to yellow |
NB-598 马来酸盐价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/08 | HY-16343C | NB-598 马来酸盐 NB-598 Maleate | 155294-62-5 | 2mg | 1214元 |
| 2024/11/08 | HY-16343C | NB-598 马来酸盐 NB-598 Maleate | 155294-62-5 | 5mg | 1560元 |
| 2024/11/08 | HY-16343C | NB-598 马来酸盐 NB-598 Maleate | 155294-62-5 | 10mM * 1mLin DMSO | 1942元 |
常见问题列表
NB-598 (10 μM) causes a 36±7% reduction in total cholesterol level of MIN6 cells. NB-598 causes a significant decrease in cholesterol by 49±2%, 46±7%, and 48±2% from PM, ER, and SG, respectively. NB598 at concentrations up to 10 μM does not affect peak outward KV currents or the voltage dependence of activation but increases current inactivation. NB-598 (10 μM) inhibits the synthesis of sterol and sterol ester from [ 14 C]acetate without affecting the synthesis of other lipids such as phospholipids (PL), free fatty acids (FFA) and triacylglycerol (TG). In the absence of exogenous liposomal cholesterol, NB-598 reduces ACAT activity by 31%. NB-598 reduces ACAT activity by 22% even in the presence of a 600 PM concentration of liposomal cholesterol. NB-598 suppresses the secretion of cholesterol and triacylglycerol from HepG2 cells into the medium.