1462383-00-1

MK319 is an AKR1B10 inhibitor. AKR1B10 has evolved as a tumor marker and promising antineoplastic target. It shares high structural similarity with the diabetes target enzyme aldose reductase (AR).

MK 319 是一种选择性的醛糖还原酶 (AR) 抑制剂，其 IC50 值为 0.3 μM。MK 319 可用于糖尿病研究。