1354030-51-5
中文名称
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
英文名称
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
CAS
1354030-51-5
分子式
C21H22Cl2N2OS
分子量
421.383
MOL 文件
1354030-51-5.mol
结构式
基本信息
中文别名
化合物 T29065
英文别名
UNC9994
UNC-9994
UNC 9994
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
UNC-9994
UNC 9994
5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
应用领域
用途一
UNC9994 is a β-arrestin-biased dopamine D? receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%). UNC9994 has robust in vivo antipsychotic drug-like activities. Functionally selective G protein-coupled receptor (GPCR) ligands, which differentially modulate canonical and noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essential for both the therapeutic actions and side effects of drugs.