1070424-33-7

BIPM novel and potent Rho-associated protein kinase 2 (ROCK2) inhibitor. Exposure of SH-SY5Y cells to BIPM led to significant changes in neurite length, cell migration and actin stress fibers. Further experiments demonstrated that BIPM was able to significantly inhibit phosphorylation of cofilin, a regulatory protein of actin cytoskeleton.

BIPM 是一种有效的 ROCK2 抑制剂。BIPM 导致神经突长度、细胞迁移和肌动蛋白应力纤维发生显著变化。BIPM 在抗癌症转移中起着重要作用。