1000578-26-6
基本信息
(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN
2-Naphthalenamine, 1,2,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-, (2S)-
物理化学性质
| 沸点 | 413.3±45.0 °C(Predicted) |
| 密度 | 1.09±0.1 g/cm3(Predicted) |
| 储存条件 | Desiccate at -20°C |
| 溶解度 | <28.34mg/ml in ethanol; <28.34mg/ml in DMSO |
| 酸度系数(pKa) | 9.20±0.20(Predicted) |
| 形态 | oil |
| 颜色 | 深黄色 |
(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-103142 | AS19 | 1000578-26-6 | 1 mg | 2320元 |
| 2026/09/15 | HY-103142 | (2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN AS19 | 1000578-26-6 | 5mg | 4700元 |
| 2026/09/15 | HY-103142 | (2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN AS19 | 1000578-26-6 | 10 mM * 1 mLin DMSO | 5170元 |
常见问题列表
|
Human 5-HT 7 Receptor 0.83 nM (IC 50 ) |
Human 5-HT 7 Receptor 0.6 nM (Ki) |
5-HT 1A Receptor 89.7 nM (Ki) |
5-HT 1B Receptor 490 nM (Ki) |
5-HT 1D Receptor 6.6 nM (Ki) |
5-HT 5 Receptor 98.5 nM (Ki) |
The proliferation of T-cell from parachlorophenylalanine-treated mice is significantly reduced, addition of AS19 (1 μM) completely restores T-cell proliferation after 48 hours.
AS19 (0.5-10 mg/kg; subcutaneous injection; for 24 hours; male Wistar rats) treatment improves memory consolidation in an autoshaping Pavlovian/instrumental learning task.
| Animal Model: | Male Wistar rats (12-week-old) with autoshaping Pavlovian/instrumental learning task |
| Dosage: | 0.5 mg/kg, 1 mg/kg, 5 mg/kg, 10 mg/kg |
| Administration: | Subcutaneous injection; for 24 hours |
| Result: | Enhanced memory formation in an autoshaping Pavlovian/instrumental learning task. |