99599-78-7

Name	E 0747
CAS	99599-78-7
Molecular Formula	C21H28ClN3O4
MDL Number	MFCD01939145
Molecular Weight	421.918
MOL File	99599-78-7.mol

Synonyms

E 0747 L-29065 6-chloro-2,2-dimethyl-1'-[3-(4-hydroxypiperidino)propyl]spiro[chroman-4,4'-imidazolidine]-2',5'-dione 6-Chloro-2,3-dihydro-1'-[3-(4-hydroxy-1-piperidinyl)propyl]-2,2-dimethylspiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione

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Hazard Information

Description

E 0747 is an antiarrhythmic agent of class 1C type of the Vaughan Williams' classification. E-0747 suppresses arrhythmia by inhibiting Na channels of cardiac cells and is expected to become a clinically useful antiarrhythmic drug.

Uses

E-0747 is an antiarrhythmic drug that inhibits arrhythmias by inhibiting Na[+] channels in cardiomyocytes[1].

References

[1] Mitsuhashi H, et al. Antiarrhythmic effects of a new drug, E-0747, on canine ventricular arrhythmia models. Jpn J Pharmacol. 1987 Jun;44(2):155-62. DOI:10.1254/jjp.44.155

Spectrum Detail

E 0747(99599-78-7)¹HNMR

Supplier

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shanghai Amole Biotechnology Co., Ltd.

Telephone18916360931 18916360931

Websitehttps://www.amole.com.cn/

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