99586-66-0

2-Amino-4-chloro-6-methylpyrimidine-5-carbonitrile is a useful reactant for research.

In a 100 mL round bottom flask, 4-chloro-6-methylpyrimidin-2-amine (3 g, 21.0 mmol) was dissolved in 40 mL of glacial acetic acid and cooled in an ice bath to less than 10°C. The reaction was carried out in an ice bath. To the upper solution was added NIS