7-Bromo-2-chloroquinoline (2) was used as starting material and reacted with sodium methanol to prepare 7-bromo-2-methoxyquinoline (1) in 98% yield. The melting point of the product was 68-69 °C. The nuclear magnetic resonance hydrogen spectrum (1H NMR, 300 MHz, CDCl3) data were as follows: δ 8.05 (d, 1H, J = 1.8 Hz), 7.93 (d, 1H, J = 8.7 Hz), 7.57 (d, 1H, J = 9.0 Hz), 7.47 (dd, 1H, J = 8.7 Hz, 1.8 Hz), 6.91 (d, 1H, J = 9.0 Hz), 4.00 (s, 3H). The mass spectrum (MS, APCI, pos. 30V) showed a molecular ion peak m/z of 239.06 ([M + H]+).
