Chemical Properties
GOLDEN YELLOW TO DARK RED CRYSTALLINE POWDER
Uses
1,1'-Diethyl-2,2'-cyanine Iodide is a potent inhibitor of potent extraneuronal monoamine transporter EMT. It inhibits 1-Methyl-4-phenylpyridinium (MPP+), toxic metabolite of 1-methyl-4-phenyl-1,2,3,6-
tetrahydropyridine that induces apoptosis in cerebellar granule neurons (CGNs).
Definition
ChEBI: 1,1'-diethyl-2,2'-cyanine iodide is a 1,1'-diethyl-2,2'-cyanine halide and an organic iodide salt.
General Description
1,1′-Diethyl-2,2′-cyanine iodide is a quinocyanine dye. This photographic sensitizing dye is mainly used in silver halide photography. 1,1′-Diethyl-2,2′-cyanine iodide dye aggregation in dilute aqueous solution displays red and blue shifted absorption bands.
Purification Methods
It crystallises from EtOH and is dried in a vacuum oven at 80o for 4hours. [Beilstein 23 II 267.]
