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Treating diabetic mice with menhaden oil in the diet or exogenously with resolvins D1 and E1 or the methyl esters of resolvins D1 (1 ng/g ; i.p.; daily) and D2 reduced triglyceride levels to control values or lower in type 2 diabetes C57BL/6J mice^[1].
Treating diabetic mice with the methyl esters of resolvins D1 or D2 significantly improved motor nerve conduction velocity compared to non-treated diabetic mice but both motor and sensory nerve conduction velocities in these treated mice remained significantly impaired compared to control mice^[1].