Tec-IN-6 is a Tec kinase inhibitor. Tec-IN-6 also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).
Uses
Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC50 of 8.9 μM (His-FGF2/GST-NΔ173 Tec)[1].
References
[1] Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291(34):17787-803. DOI:10.1074/jbc.M116.729384
