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Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora. It inhibits IL-1β-induced microsomal prostaglandin E₂ synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM. It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM.

Garcinoic Acid displays anti-angiogenic activity as well as anti-oxidative activity in animals.

Natural product derived from plant source.

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