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6-Carboxytetramethylrhodamine is a fluorescent dye that has commonly been used for the covalent labeling of oligonucleotides for DNA analysis. It displays excitation/emission maxima of 543/572 nm, respectively. 6-Carboxytetramethylrhodamine has been used in various DNA-protein binding studies, DNA FRET experiments, and as a standard reporter or quencher dye in RT-PCR.

Grey Solid

A long-wavelength dye

Free acid form of 6-carboxytetramethylrhodamine single isomer.

[1] MAKSIM V. KVACH. Practical Synthesis of Isomerically Pure 5- and 6-Carboxytetramethylrhodamines, Useful Dyes for DNA Probes[J]. Bioconjugate Chemistry Bioconjugate, 2009, 20 8: 1673-1682. DOI: 10.1021/bc900037b
[2] CHENGLING HAN  Lily Z  Tingting Chen. Terbium chelate as donor label in time-resolved fluorescence energy transfer study of DNA hybridization[J]. Chemical Physics Letters, 2010, 500 4: Pages 323-326. DOI: 10.1016/j.cplett.2010.10.028

540 nm/568 nm