Synthesis of potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate (19b): potassium triethylsilanolate (411 mg, 3.20 mmol) was suspended in ethyl ether at room temperature and stirred to form a slurry. Subsequently, ethyl 5-methyl-1,3,4-oxadiazole-2-carboxylate (0.50 g, 3.20 mmol) was added at once. The reaction immediately produced a precipitate, which changed color from white to off-white. The precipitate was separated by filtration, washed with ether and dried to give the title compound as an off-white solid (580 mg, quantitative yield).1H NMR (300 MHz, CDCl3): δ 2.61 (3H, s). 13C NMR (75 MHz, D2O): δ 166.7, 161.3, 159.3, 10.4.
![5-METHYL-[1,3,4]OXADIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER](/CAS/GIF/37641-36-4.gif)
