871982-52-4

Roquefortine E is an analog of Roquefortine C and antimitotic agent. Naturally occuring diketopiperazine antibacterial compound isolated from Australian soil isolate of the ascomycete G. reesii.

Roquefortine E is an analogue of Roquefortine C, containing an additional isoprenyl unit on the imidazole similar to phenylhistin, a recently described antimitotic agent. Roquefortine E is a selective, albeit weakly active, antitumour agent.