869802-44-8

A-794282 is a selective mGluR1 antagonist.

A-794282 is a compound with analgesic activity and is a selective mGlu1 receptor antagonist that significantly reduces pain behaviors in a postoperative pain model, but motor side effects may occur at higher doses.

mGluR1

[1] Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats DOI:10.1016/j.ejphar.2007.09.047
[2] [Research progress of selective mGluR1 antagonists] PMID:22242445