869705-22-6

Obestatin(rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. Obestatin(rat) suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin(rat) has anti-inflammatory, anti-myocardial infarction and antioxidant activities[1][2].

[1] Azadeh Toosi, et al. Obestatin Improve Spatial Memory Impairment in a Rat Model of Fetal Alcohol Spectrum Disorders via Inhibiting Apoptosis and Neuroinflammation. Neuropeptides. 2019 Apr;74:88-94. DOI:10.1016/j.npep.2019.01.001
[2] Science. 2005 Nov 11;310(5750):996-9. doi: 10.1126/science.1117255. DOI:10.1126/science.1117255