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Resolvin E2 is a potent antiinflammatory compound derived from the omega-3 polyunsatrated fatty acid eicosapentaenoic acid (EPA). Resolvin E2 was shown to be biologically active in blocking neutrophil infiltration and reducing proinflammatory cytokines in the acute peritonitis model.

Resolvin E2 is a potent antiinflammatory compound derived from the omega-3 polyunsatrated fatty acid eicosapentaenoic acid (EPA). Resolvin E2 was shown to be biologically active in blocking neutrophil infiltration and reducing proinflammatory cytokines in the acute peritonitis model.

ChEBI: Resolvin E2 is a member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18R stereoisomer). It has a role as an anti-inflammatory agent, a human xenobiotic metabolite and a rat metabolite. It is a resolvin, a diol, a secondary allylic alcohol and a hydroxy polyunsaturated fatty acid. It is a conjugate acid of a resolvin E2(1-).