ChemicalBook CAS DataBase List 854601-60-8

854601-60-8

Name	3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
CAS	854601-60-8
Molecular Formula	C23H49NO11
MDL Number	MFCD27977521
Molecular Weight	515.64
MOL File	854601-60-8.mol

Chemical Properties

Boiling point	551.9±45.0 °C(Predicted)
density	1.070±0.06 g/cm3(Predicted)
form	Solid-Liquid Mixture
pka	8.74±0.10(Predicted)
color	Colorless to off-white

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Hazard Information

Description

m-PEG11-amine is a water soluble PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

M-PEG11-Amino is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

target

Supplier

Shandong Xiya Chemical Co., Ltd

Telephone4009903999 13355009207

Websitehttp://www.xiyashiji.com

Daicel Chiral Technologies (China)CO.,LTD

Telephone021-50460086-9 15921403865

Websitehttp://www.daicelchiraltech.cn/reagents/Default.aspx

T&W GROUP

Telephone021-61551611 13296011611

Websitehttp://www.trustwe.com/

Nanjing Norris-Pharm Technology Co., Ltd

Telephone 13901585132

Website

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Telephone400-400-6206333 18521732826

Websitehttp://www.aladdin-e.com/

Nanjing Anyan Pharmaceutical Technology Co. , Ltd.

Telephone025-58361178 17351780683

Websitehttps://www.chemicalbook.com/productlist.aspx?cbn=CB0386760

Shanghai JONLN Reagent Co., Ltd.

Telephone400-0066400 13621662912

Websitehttp://www.jonln.com

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Telephone 400-8592883 15367835770

Websitehttp://www.huatengsci.com

Shanghai Boka-chem Tech. Inc.

Telephone400-026-1533/(021) 6478-0600

Websitehttp://www.bokachem.com

AN PharmaTech Co Ltd

Telephone86(21)68097365

Websitehttp://www.anpharma.net

Tongling HengYou Biotechnology Co., Ltd.

Telephone021-50426030 13856289449

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList16800/0.htm

Codow Chemical Co.,Ltd.

Telephone 18620099427

Websitehttp://www.howeipharm.com

Chengdu Dianchun Technology Co., Ltd

Telephone400-1166-196 18502815961

Websitehttp://www.hx-r.com

ShangHai Biochempartner Co.,Ltd

Telephone177-54423994 17754423994

Websitehttps://www.biochempartner.com

Jinan elephant international trading co., LTD

Telephone

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList19883/0.htm

Amadis Chemical Company Limited

Telephone571-89925085

Websitehttp://www.amadischem.com

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840 18892239720

Websitehttp://www.jm-bio.com/

Zhengzhou Huiju Chemical Co., Ltd.

Telephone0371-55900031 18137872243

Websitehttps://www.chemicalbook.com/supplier/11124122/

1of4

Related Products

Send Inquriy

Cleavable

PEGs