853-23-6

Name	Dehydroepiandrosterone acetate
CAS	853-23-6
EINECS(EC#)	212-714-1
Molecular Formula	C21H30O3
MDL Number	MFCD00021119
Molecular Weight	330.46
MOL File	853-23-6.mol

Chemical Properties

Melting point	168-170 °C(lit.)
Boiling point	407.89°C (rough estimate)
density	1.0998 (rough estimate)
vapor pressure	0Pa at 20℃
refractive index	1.5192 (estimate)
storage temp.	Refrigerator
solubility	Chloroform, DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
optical activity	[α]20/D +2.4°, c = 2 in ethanol
Water Solubility	11.5mg/L(temperature not stated)
InChI	InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
InChIKey	NCMZQTLCXHGLOK-KJBVPOJVSA-N
SMILES	C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] \|&1:1,4,13,15,21,25,r\|
LogP	5.1 at 20℃
CAS DataBase Reference	853-23-6

Safety Data

Safety Statements	22-24/25 less more
WGK Germany	3
RTECS	BV8396810

Raw materials And Preparation Products

Hazard Information

Chemical Properties

Off-White Solid

Uses

A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function

Uses

Menopausal syndrome

Definition

ChEBI:Prasterone acetate is a steroid ester.

Flammability and Explosibility

Notclassified

Biological Activity

Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.

in vivo

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

storage

Store at -20°C

Spectrum Detail

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