84625-50-3

Take 1kg of dried coltsfoot flower buds and crush them, add 4L petroleum ether (distillation range 60-90°C), soak at room temperature for 5h, ultrasonically extract 3 times, 60min each time, filter the extract, and concentrate to dryness under reduced pressure to obtain 1.31g of extract, namely An extract of coltsfoot flower for asthma treatment.

1. Antitussive effect: coltsfoot flower has antitussive effect, and ether extract has antispasmodic effect on bronchospasm caused by histamine, but the effect Weaker than aminophylline.
2. Expectorant effect: Animal experiments have shown that coltsfoot decoction can promote the increase of respiratory secretions, and has obvious expectorant effect.
3. Effect on smooth muscle: The ether extract of coltsfoot flower has inhibitory effect on gastrointestinal smooth muscle in vivo and in vitro.
4. Effects on blood pressure: Coltsfoot alcohol extract has the effect of first reducing and then increasing blood pressure.