ChemicalBook CAS DataBase List 838819-70-8

838819-70-8

Name	3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-
CAS	838819-70-8
Molecular Formula	C26H22FN3O3
Molecular Weight	443.47
MOL File	838819-70-8.mol

Chemical Properties

Boiling point	679.4±55.0 °C(Predicted)
density	1.283±0.06 g/cm3(Predicted)
form	Solid
pka	13.53±0.46(Predicted)
color	Off-white to light yellow

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Animal Model:	Wild-type C57BL/6J mice and NCX-KO mice^[2]
Dosage:	0.1, 0.3 and 1 mg/kg
Administration:	Oral administration, once
Result:	Caused a dose-dependent increase (up to approximately 200%) in urine volume and urinary excretion of electrolytes (Na⁺, K⁺ and Cl^-). Natriuretic actions were equivalently observed in NCX1-KO and WT, but disappeared in NCX2-KO and double KO.

838819-70-8

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