82972-54-1

Diazoketone methotrexate is an analogs of methotrexate, and a potential antitumor agent.

Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate[1].

[1] Gangjee A, et al. Diazoketone and chloromethylketone analogs of methotrexate as potential antitumor agents. J Pharm Sci. 1982 Jun;71(6):717-9. DOI:10.1002/jps.2600710631