79172-04-6

8-Epiloganin can be isolated from Castilleja rubra and has anti-inflammatory properties. 8-Epiloganin inhibits LPS-induced release of pro-inflammatory cytokines, namely tumor necrosis factor-α and interleukin-1β[1].

[1] Lee DS, et al. Secondary metabolites isolated from Castilleja rubra exert anti-inflammatory effects through NF-κB inactivation on lipopolysaccharide-induced RAW264.7 macrophages. Arch Pharm Res. 2014 Jul;37(7):947-54. DOI:10.1007/s12272-013-0243-y