760952-88-3

THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. THPTA is a superior alternative to water-insoluble TBTA. a) J. Am. Chem. Soc. 2011, 133, 17993. b) Bioconjugate Chem. 2010, 21, 1912.

Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst.

Store at -20°C