7398-42-7

4-(Bromomethyl)phenylacetic acid phenacyl ester has reactive groups that allow it to be conjugated to amino acids or peptides with free amine or carboxylic acid groups.

4-(Bromomethyl)phenylaceticacidphenacylester is used in the laboratory for the detection of protein-protein interactions. It can be conjugated to a protein target, such as human serum albumin, and then used as a hydrogen bond donor in an assay.

4-(Bromomethyl)phenylaceticacidphenacylester is synthesized by reacting 4-(bromomethyl)phenylacetic acid with phenacyl bromide and potassium carbonate in chloroform.

[1] Patent: WO2014/66659, 2014, A1. Location in patent: Paragraph 0616
[2] Patent: EP1939199, 2008, A1. Location in patent: Page/Page column 96-97
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[4] Patent: WO2015/137750, 2015, A1. Location in patent: Paragraph 710; 711
[5] Patent: WO2013/171281, 2013, A1. Location in patent: Page/Page column 169