7336-33-6

Name (-)-3-Demethylcolchicine
CAS 7336-33-6
Molecular Formula C21H23NO6
MDL Number MFCD00866366
Molecular Weight 385.41
MOL File 7336-33-6.mol

Chemical Properties

Melting point  163-166°C
Boiling point  768.3±60.0 °C(Predicted)
density  1.31±0.1 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  DMSO : 100 mg/mL (259.46 mM; Need ultrasonic)
form  A solid
pka 9.53±0.40(Predicted)
color  White to yellow
InChI InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-17(25)20(27-3)21(28-4)19(12)13-6-8-18(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1
InChIKey JRRUSQGIRBEMRN-HNNXBMFYSA-N
SMILES C(N[C@@H]1C2C(C3=C(OC)C(OC)=C(O)C=C3CC1)=CC=C(OC)C(=O)C=2)(=O)C

Safety Data

Symbol(GHS)  Health Hazard (GHS08)Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS08,GHS05,GHS06
Signal word  Danger
Hazard statements  H318-H330-H300-H340
Precautionary statements  P280-P305+P351+P338-P310-P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
Toxicity
LD50 intraperitoneal in mouse: 570ug/kg

Hazard Information

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