725474-97-5

Endogenous truncated form of the incretin hormone GIP. More potent at stimulating glucose-dependent insulin secretion from rat pancreaticβ-cells than GIP.

GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) is an insulinotropic peptide that stimulats insulin secretion from rat pancreatic islets. GIP (1-39) at 100 nM was able to significantly increase intracellular Ca2+ concentration ([Ca2+]i), and capable of enhancing exocytosis[1].

Desiccate at -20°C

[1] Xie L, et al. GIP1-39, a novel insulinotropic peptide form and aspects on its mechanism of action. Regul Pept. 2004 Sep 15;121(1-3):107-12. DOI:10.1016/j.regpep.2004.04.013