68890-65-3

Intralipid (2 g/kg) does not affect phagocytosis and may promote macrophage polarization to the M1 phenotype, as observed in breast cancer tumor sections from Balb/c mice^[1].
Intralipid pretreatment promotes the accumulation of paclitaxel in tumour tissue and induces higher levels of apoptosis in tumour cells. Increased distribution of paclitaxel in mouse RES organs and enhanced inhibition of tumour growth^[1].
Intralipid (5 mL/kg) is more effective than cyclosporin-A in protecting the heart from I/R injury in SD rats, reducing the size of myocardial infarction by approximately 40%^[2].