68054-78-4

2-(Cyclohexylamino)-5-(phenylamino)-2,5-cyclohexadiene-1,4-dione is a useful reagent for organic synthesis processes. It is used in the preparation of 1,4-benzoquinones or p-quinones, which are archetypical members of the quinoid family that attracts interest across various disciplines with wide applications and relevance in the fields of dyes, functional materials, biointerfaces, ligands, redox processes, pharmacology and toxicology.

[1] WEI WANG . Toxicity of substituted p-phenylenediamine antioxidants and their derived novel quinones on aquatic bacterium: Acute effects and mechanistic insights[J]. Journal of Hazardous Materials, 2024, 469: Article 133900. DOI: 10.1016/j.jhazmat.2024.133900
[2] WANG Y, LIANG G, CHAO J, et al. Comparison of intestinal toxicity in enhancing intestinal permeability and in causing ROS production of six PPD quinones in Caenorhabditis elegans.[J]. The Science of the total environment, 2024, 495 1: 172306. DOI: 10.1016/j.scitotenv.2024.172306
[3] WEI WANG, ZONGWEI CAI*   Beyond Substituted p-Phenylenediamine Antioxidants: Prevalence of Their Quinone Derivatives in PM2.5[J]. 环境科学与技术, 2022, 56 15: 10629-10637. DOI: 10.1021/acs.est.2c02463