661-19-8

Name 1-Docosanol
CAS 661-19-8
EINECS(EC#) 211-546-6
Molecular Formula C22H46O
MDL Number MFCD00002939
Molecular Weight 326.6
MOL File 661-19-8.mol

Chemical Properties

Definition A long-chain, saturated fatty alcohol.
Appearance white powder
Melting point  65-72 °C(lit.)
Boiling point  180 °C0.22 mm Hg(lit.)
density  d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml
vapor pressure  0Pa at 25℃
refractive index  n75 1.4360
storage temp.  2-8°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly)
form  Pellets or Tablets
pka 15.20±0.10(Predicted)
color  White
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility  Insoluble
Merck  13,3433
BRN  1770470
Henry's Law Constant 6.2×10-3 mol/(m3Pa) at 25℃, HSDB (2015)
Cosmetics Ingredients Functions SKIN CONDITIONING - EMOLLIENT
BINDING
VISCOSITY CONTROLLING
EMULSION STABILISING
Cosmetic Ingredient Review (CIR) n-Docosanol (661-19-8)
InChI 1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
InChIKey NOPFSRXAKWQILS-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCCCCCCCCCCCO
LogP 8.3 at 20℃
Uses
behenyl alcohol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants.
CAS DataBase Reference 661-19-8(CAS DataBase Reference)
NIST Chemistry Reference 1-Docosanol(661-19-8)
EPA Substance Registry System 661-19-8(EPA Substance)

Safety Data

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H410-H319
Precautionary statements  P273-P391-P501-P264-P280-P305+P351+P338-P337+P313P
Safety Statements 
S24/25:Avoid contact with skin and eyes .
WGK Germany  -
RTECS  JR1315000
TSCA  Yes
REACH Registrations Active
HS Code  29051900
Storage Class 11 - Combustible Solids
Hazardous Substances Data 661-19-8(Hazardous Substances Data)
Toxicity
LD50 intraperitoneal in mouse: > 800mg/kg

Hazard Information

Material Safety Data Sheet(MSDS)

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