65307-12-2

Name	Cefetrizole
CAS	65307-12-2
Molecular Formula	C16H15N5O4S3
MDL Number	MFCD00864923
Molecular Weight	437.52
MOL File	65307-12-2.mol

Synonyms

Cefetrizole (6R,7R)-8-Oxo-7-[2-thienylacetylamino]-3-[(1H-s-triazol-3-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[[2-(2-thienyl)acetyl]amino]-3-[(1H-1,2,4-triazol-5-ylthio)methyl]-, (6R,7R)-

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Chemical Properties

density	1.71±0.1 g/cm3(Predicted)
pka	2.65±0.50(Predicted)

Hazard Information

Biological Activity

Ceftezole is an α-Glucosidase inhibitor with IC50 and Ki values of 2.1 μM and 0.578 μM, respectively.

in vitro

In in vitro α-Glucosidase assays, Ceftezole is shown to be a reversible, non-competitive inhibitor of yeast α-glucosidase with a K _i value of 5.78×10 ^-7 M when the enzyme mixture is pretreated with ceftezole.

target

IC50: 2.1 μM (α-Glucosidase)
Ki: 0.578 μM (α-Glucosidase)

Supplier

Hangzhou changru chemical co., ltd

Telephone 18453016280

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1493175/0.htm

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840

Websitehttp://www.jm-bio.com/

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Hangzhou MolCore BioPharmatech Co.,Ltd.

Telephone+86-057181025280; +8617767106207

Websitehttps://www.molcore.com/

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