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Cyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. It acts as a stabilizing agent and facilitates various catalytic reactions. This compound finds applications in pharmaceuticals, fine chemicals, and materials science industries. Cyclohexyldiphenylphosphine should be handled with caution as it may cause skin and eye irritation. It should be stored in a cool, well-ventilated area away from heat sources or open flames. Proper personal protective equipment (PPE) should be worn when handling this compound. Not for human consumption. Such as Silver(I) phosphine complexes were synthesized by a reaction of AgNO3, AgCl, and AgBr with cyclohexyl diphenylphosphine to produce 1:1, 1:2, or 1:3 molar ratios of new silver complexes[1].

white to light yellow crystal powde

suzuki reaction

Cyclohexyldiphenylphosphine can undergo complexation reactions with common transition metals and can be used to catalyze a variety of organic transformation reactions including Suzuki coupling reactions and metal-catalyzed Michael addition reactions.

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

[1] Naganagowda, Gadada et al. “Synthesis, crystal structure and spectral studies of silver(I) cyclohexyldiphenylphosphine complexes: towards the biological evaluation on malignant and non-malignant cells.” Journal of Coordination Chemistry 21 1 (2023): 0.