Lithium chloroacetylide is a nucleophilic organolithium reagent that reacts with a variety of electrophiles.
Preparation
Lithium chloroacetylide is prepared in ether solution under anhyd conditions by treatment of cis- or trans-1,2- dichloroethylene with 2 equiv Methyllithium at 0 °C under N2.
storage
Dry lithium chloroacetylide is explosive (as are the other metal haloacetylides), but may be safely handled and kept in the solution in which it is prepared under N2.
