6119-47-7

Name Quinine hydrochloride dihydrate
CAS 6119-47-7
EINECS(EC#) 231-437-7
Molecular Formula C20H29ClN2O4
MDL Number MFCD00151248
Molecular Weight 396.91
MOL File 6119-47-7.mol

Chemical Properties

Appearance white to light yellow crystal powde
Melting point  115-116 °C (dec.)(lit.)
alpha  [α]D20 -245~-255° (c=2, dil. HCl) (After Drying)
bulk density 310kg/m3
FEMA  2976
refractive index  -250 ° (C=2, EtOH)
Fp  122 °C
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  H2O: soluble0.25/5g/mL, clear, colorless
form  Crystalline Powder or Silky Needles
color  White to off-white
Odor odorless
PH 6.0 (10g/l, H2O, 20℃)
Odor Type odorless
Optical Rotation [α]22/D 235°, c = 2 in 0.1 M HCl
Water Solubility  Sparingly soluble in water.(0.26 g/L) (25°C),
Sensitive  Light Sensitive
Merck  8061
BRN  6112655
InChIKey MPQKYZPYCSTMEI-HPVDNOPASA-N
SMILES O.O.Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
Uses
Antiprotozoal (malaria).
CAS DataBase Reference 6119-47-7(CAS DataBase Reference)
Storage Precautions Light sensitive

Safety Data

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H317-H334
Precautionary statements  P261-P264-P270-P280-P301+P312-P302+P352
Hazard Codes  Xn,Xi
Risk Statements 
R22:Harmful if swallowed.
R42/43:May cause sensitization by inhalation and skin contact .
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Statements 
S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
RIDADR  1544
WGK Germany  3
RTECS  VA7700000
8
Hazard Note  Irritant
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Resp. Sens. 1
Skin Sens. 1
Toxicity
LD50 orally in Rabbit: 620 mg/kg

Hazard Information

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