580-20-1

3054-95-3

591-27-5

580-20-1

The general procedure for the synthesis of 7-hydroxyquinoline from acrolein diethyl acetal and 3-aminophenol was as follows: the reaction was carried out in a Panasonic NN-K5541JF microwave reactor equipped with a magnetic stirring device. The typical operation was as follows: acrolein diethyl acetal (1 mmol), excess 3-aminophenol (4 mmol) and solid catalyst were added to a round bottom flask; subsequently, the mixture was placed in a microwave reactor. The reaction was carried out by continuous microwave radiation under reflux and stirring conditions for 1 to 40 min. Upon completion of the reaction, the products were analyzed and identified using a Varian Saturn 2200/CP-3800 gas chromatography-mass spectrometer (GC-MS) equipped with two CP8944 capillary columns (VF-5, 30 m × 0.25 mm × 0.25 μm).