ChemicalBook CAS DataBase List 57564-91-7

57564-91-7

Name	S-NITROSOGLUTATHIONE
CAS	57564-91-7
EINECS(EC#)	248-170-7
Molecular Formula	C10H16N4O7S
MDL Number	MFCD00214341
Molecular Weight	336.32
MOL File	57564-91-7.mol

Chemical Properties

Appearance	Pink Powder
Melting point	>170°C (dec.)
density	1.68
refractive index	1.6000 (estimate)
storage temp.	−20°C
solubility	DMSO (Slightly), Water (Slightly)
form	Pink solid
pka	2.21±0.10(Predicted)
color	Off-White to Pink
Water Solubility	Soluble to 100 mM in water
Usage	A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation
Stability:	Hygroscopic
CAS DataBase Reference	57564-91-7(CAS DataBase Reference)

Safety Data

Hazard Codes	Xi
Risk Statements	R36/37/38:Irritating to eyes, respiratory system and skin . less more
Safety Statements	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . less more
WGK Germany	3
RTECS	MC0558000

Hazard Information

Description

S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.

Chemical Properties

Pink Powder

Uses

S-Nitrosoglutathione (GSNO) has been used:

as a standard in reversed phase chromatography coupled to chemical vapour generation and atomic fluorescence detector (RPC-CVGAFS) and reversed phase chromatography fluorimetric (RPC-FD).
as a standard in spectrophotometric and high-performance liquid chromatography (HPLC) assay.

Uses

A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation

Definition

ChEBI: S-nitrosoglutathione is a glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by a nitroso group. It has a role as a platelet aggregation inhibitor, a bronchodilator agent, a nitric oxide donor and a signalling molecule. It is a glutathione derivative and a nitrosothio compound. It is a conjugate acid of a S-nitrosoglutathione(2-).

General Description

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Biological Activity

A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.

Biochem/physiol Actions

Product does not compete with ATP.

storage

Desiccate at -20°C

Spectrum Detail

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