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MT-45 (hydrochloride) (CRM) (Item No. 19737) is a certified reference material categorized as an opioid. It is a novel synthetic opioid that has analgesic activity similar to morphine in animal models. MT-45 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

MT-45 is a piperazine derivative with potent analgesic activity comparable to morphine. It has been used as a lead compound to develop a large group of potent opioid drugs with agonist or antagonist activities particular to the various opioid receptor subtypes.

MT-45, also known as IC-6, is a piperazone derivative with analgesic activity comparable to morphine. According to a recent report released by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), MT-45 has been associated with deaths in the United States and Sweden, since it emerged on the illicit drug market in 2013. This Certified Spiking Solution^? is suitable as starting material for calibrators or controls in MT-45 GC/MS or LC/MS methods for urine drug testing, forensic analysis, or clinical toxicology applications.

[1] MICHAEL H. BAUMANN . Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace[J]. Neuropharmacology, 2018, 134: Pages 101-107. DOI: 10.1016/j.neuropharm.2017.08.016