54193-28-1

A metabolite of Doxorubicin as neoplasm inhibitor.

ChEBI: Doxorubicinol is a member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties. It has a role as a drug metabolite and a cardiotoxic agent. It is a member of p-quinones, an anthracycline antibiotic, a deoxy hexoside, an aminoglycoside, a member of tetracenequinones, a member of phenols, an aromatic ether and a polyol. It derives from a hydride of a tetracene.

Adriamycin fermentation broth 2000 liters, add 1N of hydrochloric acid adjusted pH 1.0 for acidification, acidification 3 hours, plate and frame filtration, to get the pre-purified solution 1650 liters, HPLC detection, containing 1000g of adriamycin, chro