5267-37-8

3-chlorobenzophenone (43.33g, 0.2 mol) and ammonium formate (63.06g, 1.0 mol) were refluxed for 3 hours in nitrobenzene (250 ml). After cooling the refluxed mixture to room temperature, the reaction solution was concentrated in vacuo. The 15% HCl-ethanol solution (420 ml) was added to the residue, and the mixture was refluxed for 2 hours. Then the reaction solution was concentrated in vacuo. Thereafter, the diethyl ether was added. Finally, C-(3-CHLORO-PHENYL)-C-PHENYL-METHYLAMINE HYDROCHLORIDE was obtained by filtration.