ChemicalBook CAS DataBase List 510774-50-2

510774-50-2

Name	8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
CAS	510774-50-2
Molecular Formula	C17H17ClN5O6PS
MDL Number	MFCD04974491
Molecular Weight	485.84
MOL File	510774-50-2.mol

Chemical Properties

Boiling point	748.9±70.0 °C(Predicted)
density	1.95±0.1 g/cm3(Predicted)
storage temp.	Desiccate at -20°C
form	White to off-white crystalline powder.
pka	0.92±0.60(Predicted)
Water Solubility	water: 10mg/mL

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Animal Model:	Wild type (WT) C57/Bl6 mice (choroidal neovascularization (CNV) model) ^[1]
Dosage:	2.05μM; 1 μL
Administration:	Intravitreal injection
Result:	Induced a slight increase in F-actin localization to the cell periphery, and reorganized cell junctions to a more linear shape, dose-dependent decreased in CNV volume, increased Rap1 activity in isolated RPE/choroids.