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Carbamoyl chloride, H2N – COCl, is unstable; it may be stabilized by Lewis acids (e.g., aluminum chloride) as adducts and in this form can be used in the Friedel-Crafts acylation of arenes. Since many of the monosubstituted carbamoyl chlorides also deteriorate on storage, the corresponding isocyanates are used instead. Disubstituted carbamoyl chlorides are stable and can be stored for prolonged periods.

The simple carbamoyl chlorides are colorless liquids or solids, usually with pungent odor.

Carbamoyl chloride can be used as an intermediate for carbamate pesticides.

ChEBI: Carbamyl chloride is an organonitrogen compound.

Carbamoyl chloride can be synthesized from methylamine and phosgene at 200-240℃.