ChemicalBook CAS DataBase List 461424-21-5

461424-21-5

Name	9H-Pyrido[3,4-b]indole, 1-(1H-imidazol-5-yl)-
CAS	461424-21-5
Molecular Formula	C14H10N4
Molecular Weight	234.26
MOL File	461424-21-5.mol

Chemical Properties

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Animal Model:	2 mg/kg LPS-induced depressive mice^[1]
Dosage:	20 mg/kg
Administration:	Intraperitoneal injection (i.p.), at day 1, 2, 3.
Result:	Attenuated microglial activation significantly. Decreased inflammatory factors in the hippocampus, such as TNF-α, IL-1β, and iNOS. Downregulated LPS-induced overexpression of IDO1.