40127-11-5

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• Preparation

  L-arginine, p-nitroaniline, and potassium carbonate were mixed, acetonitrile was added, and the mixture was heated to 80 °C for 2 h. Thin-layer chromatography analysis showed that the reaction was complete. The mixture was filtered, evaporated to dryness under reduced pressure, and the concentrate was purified by column chromatography to prepare a yellow solid H-arginine-PNA. The solid was then acidified with hydrochloric acid to prepare the target compound L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE.;

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