3859-41-4

white to cream crystalline powder

1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.

ChEBI: Cyclopentane-1,3-dione is a beta-diketone and a member of cyclopentanones.

Journal of the American Chemical Society, 102, p. 2095, 1980 DOI: 10.1021/ja00526a059

Purify the dione by Soxhlet extraction with CHCl3. The CHCl3 is evaporated and the residue is recrystallised from EtOAc and/or sublimed at 120o/4mm. [IR: Boothe et al. J Am Chem Soc 75 1732 1953, DePuy & Zaweski J Am Chem Soc 81 4920 1959, Beilstein 7 IV 1981.]