380480-75-1

ppTG20 is an amphiphilic cell penetrating peptide (KALA) that can be used for gene transfection. ppTG20 can bind to DNA, destabilize membranes, and mediate DNA transfection[1][2].

[1] Ma J, et al. Cell-penetrating peptides mediated protein cross-membrane delivery and its use in bacterial vector vaccine. Fish Shellfish Immunol. 2014 Jul;39(1):8-16. DOI:10.1016/j.fsi.2014.04.003
[2] Wyman TB, et al. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry. 1997 Mar 11;36(10):3008-17. DOI:10.1021/bi9618474