ChemicalBook CAS DataBase List 335161-24-5

335161-24-5

Name	AM2201
CAS	335161-24-5
Molecular Formula	C24H22FNO
MDL Number	MFCD16620503
Molecular Weight	359.44
MOL File	335161-24-5.mol

Synonyms

AM-2201 AM-2201 (AM 2201 AM2201 (exempt preparation) AM-2201 (1.0 mg/ml in Methanol) 1-(5-fluoropentyl)-3-(1-naphthoyl)indole 1-(5-fluoropentyl)-3-(naphtalen-1-oy)indole 1-(5-Fluoropentyl)-3-(1-naphthoyl)-1H-indole (1-(5-Fluoropentyl)-3-(naphthalen-1-oyl)indole) [1-(5-fluoropentyl)indol-3-yl]-naphthalen-1-ylmethanone [1-(5-Fluoropentyl)-1H-indol-3-yl]-1-naphthalenylmethanone 1-(5-fluoropentyl)-3-[(naphthalen-1-yl)carbonyl]-1H-indole (1-(5-fluoropentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone Methanone, [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl- [1-(5-fluoropentyl)-1H-indole-3-yl](naphthalene-1-yl)methanone (AM-2201)Methanone, [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl- AM-2201 (1-[(5-fluoropentyl)-1H-indol-3-yl]-(naphthalen-1-yl)methanone)

Chemical Properties

Boiling point	551.1±30.0 °C(Predicted)
density	1.13±0.1 g/cm3(Predicted)
storage temp.	-10 to -25°C
solubility	DMSO: 2mg/mL, clear
form	powder
color	white to beige
InChI	1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2
InChIKey	ALQFAGFPQCBPED-UHFFFAOYSA-N
SMILES	O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(C4=CC=CC=C43)CCCCCF

Safety Data

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H331-H301
Precautionary statements	P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
WGK Germany	WGK 3
Storage Class	11 - Combustible Solids
Hazard Classifications	STOT SE 3
DEA Controlled Substances	NARC:No CSA SCH:Schedule I CSCN:7201

Hazard Information

Description

AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid. AM2201 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

Chemical Properties

Pale Yellow Solid

Uses

AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively. The physiological actions and metabolism of AM2201 have not been characterized.
This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.[Cayman Chemical]

Uses

It is a drug which acts as a potent but unselective agonist for the cannabinoid receptor CB1 or CB2.

Definition

ChEBI:AM2201 is an indolecarboxamide.

References

[1] A K DUTTA. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs).[J]. Bioorganic & Medicinal Chemistry, 1997, 5 8: 1591-1600. DOI: 10.1016/s0968-0896(97)00111-9
[2] BYUNGSUK CHO . Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair[J]. Forensic science international, 2020, 306: Article 110058. DOI: 10.1016/j.forsciint.2019.110058
[3] MICHAEL A. MARINO M.S. Rapid Identification of Synthetic Cannabinoids in Herbal Incenses with DART-MS and NMR?[J]. Journal of forensic sciences, 2015, 61 S1: S82-S91. DOI: 10.1111/1556-4029.12932
[4] PH.D. L A C. Quantitation of Synthetic Cannabinoids in Plant Materials Using High Performance Liquid Chromatography with UV Detection (Validated Method)[J]. Journal of forensic sciences, 2015, 60 5: 1171-1181. DOI: 10.1111/1556-4029.12795

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