ChemicalBook CAS DataBase List 334827-98-4

334827-98-4

Name	Gisadenafil Besylate
CAS	334827-98-4
Molecular Formula	C23H33N7O5S.C6H6O3S
MDL Number	MFCD18384964
Molecular Weight	678
MOL File	334827-98-4.mol

Chemical Properties

storage temp.	Desiccate at RT
solubility	DMSO: >35mg/mL
form	powder
color	white to off-white
InChIKey	STFRDYSZKVPPQF-UHFFFAOYSA-N
SMILES	OS(=O)(=O)c1ccccc1.CCOc2ncc(cc2C3=NC(=O)c4nn(CCOC)c(CC)c4N3)S(=O)(=O)N5CCN(CC)CC5

Safety Data

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361-H412
Precautionary statements	P201-P202-P281-P308+P313-P405-P501-P273-P501
WGK Germany	3
Storage Class	11 - Combustible Solids

Hazard Information

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Animal Model:	Male Tat-transgenic (Tat-tg) mice (8 weeks old) exposed to hypercapnia^[1]
Dosage:	2 mg/kg
Administration:	Intraperitoneal injection; for 2 hours
Result:	Largely restored the normal increase in cortical flow following hypercapnia in Tat-tg mice (17.5% above baseline). Also restored the dilation of small (<25 μm) arterioles following hypercapnia.

334827-98-4

Chemical Properties

Safety Data

Hazard Information

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Biological Activity

in vivo

IC 50

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