33286-30-5

Carboxyatractyloside is a derivative of Atractyloside (A794530), a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane.

ChEBI: Carboxyatractyloside is a diterpene glycoside.